Danazol for heavy menstrual bleeding
Ann Lethaby
Treatment options to avoid surgery are important for women with heavy menstrual bleeding who want to retain their fertility. One of the drug options is danazol, which works by suppressing the hormones that increase the endometrium (the lining of the uterus that is shed during menstruation). However, danazol can also produce male characteristics and some menopause-like symptoms, as well as weight gain and acne. The review found that although danazol is effective at reducing menstrual blood loss, there are not enough trials to show whether this treatment is acceptable to women with heavy menstrual bleeding.
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